Structure of PDB 8dr5 Chain A Binding Site BS01

Receptor Information
>8dr5 Chain A (length=646) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NITAQDVLDKIPSLDLSFPEGKPNCLLGLTIVFTGVLPTLERGASEALAK
RYGARVTKSISSKTSVVVLGDEAGPKKLEKIKQLKIKAIDEEGFKQLIAG
MPAEGGDGEAAEKARRKLEEQHNIATKEAELLVKKEEERSKKLAATRVSV
VREEDKLWTVKYAPTNLQQVCGNKGSVMKLKNWLANWENSKKNSFKHAGK
DGSGVFRAAMLYGPPGIGKTTAAHLVAQELGYDILEQNASDVRSKTLLNA
GVKNALDNMSVVGYFKHNEEAQNLNGKHFVIIMDEVDGMSGGDRGGVGQL
AQFCRKTSTPLILICNERNLPKMRPFDRVCLDIQFRRPDANSIKSRLMTI
AIREKFKLDPNVIDRLIQTTRGDIRQVINLLSTISTTTKTINHENINEIS
KAWEKNIALKPFDIAHKMLDGQIYSDIGSRNFTLNDKIALYFDDFDFTPL
MIQENYLSTRPSVLKPGQSHLEAVAEAANCISLGDIVEKKIRSSEQLWSL
LPLHAVLSSVYPASKVAGHMAGRINFTAWLGQNSKSAKYYRLLQEIHYHT
RLGTSTDKIGLRLDYLPTFRKRLLDPFLKQGADAISSVIEVMDDYYLTKE
DWDSIMEFFVGPDVTTAIIKKIPATVKSGFTRKYNSMTHPVAIYRT
Ligand information
Receptor-Ligand Complex Structure
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PDB8dr5 Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Resolution2.76 Å
Binding residue
(original residue number in PDB)		G432 R434 D586 L590 R632 Q636 W669 L670
Binding residue
(residue number reindexed from 1)		G292 R294 D446 L450 R492 Q496 W529 L530
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0000278 mitotic cell cycle
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
GO:0006272 leading strand elongation
GO:0006281 DNA repair
GO:0006298 mismatch repair
GO:0051301 cell division
Cellular Component
GO:0005634 nucleus
GO:0005663 DNA replication factor C complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8dr5, PDBe:8dr5, PDBj:8dr5
PDBsum8dr5
PubMed35939393
UniProtP38630|RFC1_YEAST Replication factor C subunit 1 (Gene Name=RFC1)

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