Structure of PDB 8dqz Chain A Binding Site BS01

Receptor Information
>8dqz Chain A (length=492) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VVREEDKLWTVKYAPTNLQQVCGNKGSVMKLKNWLANWENSKKNSFKHAG
KDGSGVFRAAMLYGPPGIGKTTAAHLVAQELGYDILEQNASDVRSKTLLN
AGVKNALDNMSVVGYFKHNLNGKHFVIIMDEVDGMSGGDRGGVGQLAQFC
RKTSTPLILICNERNLPKMRPFDRVCLDIQFRRPDANSIKSRLMTIAIRE
KFKLDPNVIDRLIQTTRGDIRQVINLLSTISTTTKTINHENINEISKAWE
KNIALKPFDIAHKMLDGQIYSDIGSRNFTLNDKIALYFDDFDFTPLMIQE
NYLSTRPSVLKPGQSHLEAVAEAANCISLGDIVEKKIRSSEQLWSLLPLH
AVLSSVYPASKVAGHMAGRINFTAWLGQNSKSAKYYRLLQEIHYHTRLGT
STDKIGLRLDYLPTFRKRLLDPFLKQGADAISSVIEVMDDYYLTKEDWDS
IMEFFVGPDVTTAIIKKIPATVKSGFTRKYNSMTHPVAIYRT
Ligand information
Receptor-Ligand Complex Structure
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PDB8dqz Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Resolution2.92 Å
Binding residue
(original residue number in PDB)
R434 P461 F552 D586 F587 L590 R632 Q636 F666 W669 L670
Binding residue
(residue number reindexed from 1)
R140 P167 F258 D292 F293 L296 R338 Q342 F372 W375 L376
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0000278 mitotic cell cycle
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
GO:0006272 leading strand elongation
GO:0006281 DNA repair
GO:0006298 mismatch repair
GO:0051301 cell division
Cellular Component
GO:0005634 nucleus
GO:0005663 DNA replication factor C complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8dqz, PDBe:8dqz, PDBj:8dqz
PDBsum8dqz
PubMed35939393
UniProtP38630|RFC1_YEAST Replication factor C subunit 1 (Gene Name=RFC1)

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