Structure of PDB 8dk9 Chain A Binding Site BS01

Receptor Information

>8dk9 Chain A (length=388) Species: 1797 (Mycolicibacterium thermoresistibile) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TDLKVRLVRDDFADAVAWVARSLPSRPTVPVLAGVLLTGSDDGLTISSFD
YEVSAEVQIPAEIAAPGTVLVSGRLLSEITRALPNKPVDLSVEGTRVSLT
CGSARFSLPTMAVEDYPALPELPAETGSVPADLFAEAIGQVAVAAGRDDT
LPMLTGIRVEISGDRMVLAATDRFRLAVRELTWTTKTPDVEAAVLVPAKT
LAEAAKTGLDGSEVQLALGAGPSVGQDGLLGIRSEGKRSTTRLLDAEFPK
FRQLLPTEHTAMATIGVGELTEAIKRVALVADRGAQVRMEFADDVLHLSA
GADDVGRAEEDLPVSFSGEPLTIAFNPGYLTDGLGALHSERVTFGFTTPS
KPAVLRPATEADAALNGNGPFPAAETDYVYLLMPVRLP

Ligand information

>8dk9 Chain E (length=6) Species: 1773 (Mycobacterium tuberculosis) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

QESLFA

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	8dk9 Interaction of sliding clamp with mycobacterial polymerases
Resolution	2.5 Å
Binding residue (original residue number in PDB)	T179 R181 F182 R183 L184 P257 L262 P360 M391 P392
Binding residue (residue number reindexed from 1)	T171 R173 F174 R175 L176 P249 L254 P352 M383 P384

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003887	DNA-directed DNA polymerase activity
GO:0008408	3'-5' exonuclease activity

	Biological Process
GO:0006260	DNA replication
GO:0006271	DNA strand elongation involved in DNA replication
GO:0071897	DNA biosynthetic process

	Cellular Component
GO:0005737	cytoplasm
GO:0009360	DNA polymerase III complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:8dk9, PDBe:8dk9, PDBj:8dk9
PDBsum	8dk9
PubMed
UniProt	G7CIP4

[Back to BioLiP]