Structure of PDB 8dj6 Chain A Binding Site BS01

Receptor Information

>8dj6 Chain A (length=389) Species: 1078020 (Mycolicibacterium thermoresistibile ATCC 19527) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

LTDLKVRLVRDDFADAVAWVARSLPSRPTVPVLAGVLLTGSDDGLTISSF
DYEVSAEVQIPAEIAAPGTVLVSGRLLSEITRALPNKPVDLSVEGTRVSL
TCGSARFSLPTMAVEDYPALPELPAETGSVPADLFAEAIGQVAVAAGRDD
TLPMLTGIRVEISGDRMVLAATDRFRLAVRELTWTTKTPDVEAAVLVPAK
TLAEAAKTGLDGSEVQLALGAGPSVGQDGLLGIRSEGKRSTTRLLDAEFP
KFRQLLPTEHTAMATIGVGELTEAIKRVALVADRGAQVRMEFADDVLHLS
AGADDVGRAEEDLPVSFSGEPLTIAFNPGYLTDGLGALHSERVTFGFTTP
SKPAVLRPATEADAALNGNGPFPAAETDYVYLLMPVRLP

Ligand information

>8dj6 Chain E (length=6) Species: 1078020 (Mycolicibacterium thermoresistibile ATCC 19527) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

QLPLWG

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8dj6 Interaction of sliding clamp with mycobacterial polymerases
Resolution	2.5 Å
Binding residue (original residue number in PDB)	R181 F182 R183 P257 M391 P392 V393 R394
Binding residue (residue number reindexed from 1)	R174 F175 R176 P250 M384 P385 V386 R387

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003887	DNA-directed DNA polymerase activity
GO:0008408	3'-5' exonuclease activity

	Biological Process
GO:0006260	DNA replication
GO:0006271	DNA strand elongation involved in DNA replication
GO:0071897	DNA biosynthetic process

	Cellular Component
GO:0005737	cytoplasm
GO:0009360	DNA polymerase III complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:8dj6, PDBe:8dj6, PDBj:8dj6
PDBsum	8dj6
PubMed
UniProt	G7CIP4

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