Structure of PDB 8dhd Chain A Binding Site BS01

Receptor Information

>8dhd Chain A (length=378) Species: 243274 (Thermotoga maritima MSB8)

TKLTIWCSEKQVDILQKLGEEFKAKYGIPVEVQYVDFGSIKSKFLTAAPQ
GQGADIIVGAHDWVGELAVNGLIEPIPNFSDLKNFYDTALKAFSYGGKLY
GVPYAMEAVALIYNKDYVDSVPKTMDELIEKAKQIDEEYGGEVRGFIYDV
ANFYFSAPFILGYGGYVFKETPQGLDVTDIGLANEGAVKGAKLIKRMIDE
GVLTPGDNYGTMDSMFKEGLAAMIINGLWAIKSYKDAGINYGVAPIPELE
PGVPAKPFVGVQGFMINAKSPNKVIAMEFLTNFIARKETMYKIYLADPRL
PARKDVLELVKDNPDVVAFTQSASMGTPMPNVPEMAPVWSAMGDALSIII
NGQASVEDALKEAVEKIKAQIEKGSHHH

Ligand information

• Ligand ID: GLC
• InChI: InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
• InChIKey: WQZGKKKJIJFFOK-DVKNGEFBSA-N
• SMILES:
  OpenEye OEToolkits 1.5.0: C(C1C(C(C(C(O1)O)O)O)O)O
  OpenEye OEToolkits 1.5.0: C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
  CACTVS 3.341: OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
  CACTVS 3.341: OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
  ACDLabs 10.04: OC1C(O)C(OC(O)C1O)CO
• Formula: C6 H12 O6
• Name: alpha-D-glucopyranose;
  alpha-D-glucose;
  D-glucose;
  glucose
• ChEMBL: CHEMBL423707
• ZINC: ZINC000003861213
• PDB chain: 8dhd Chain B Residue 1

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8dhd Mapping periplasmic binding protein oligosaccharide recognition with neutron crystallography.
• Resolution: 1.7 Å
• Binding residue (original residue number in PDB): S12 E13 K14 R303
• Binding residue (residue number reindexed from 1): S8 E9 K10 R299
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:1901982 maltose binding

Biological Process

• GO:0015768 maltose transport
• GO:0034219 carbohydrate transmembrane transport
• GO:0042956 maltodextrin transmembrane transport

Cellular Component

• GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

External links

• PDB: RCSB:8dhd, PDBe:8dhd, PDBj:8dhd
• PDBsum: 8dhd
• PubMed: 36271099
• UniProt: Q9S5Y1