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PDB	8dgh NMR Structures of Calmodulin Bound to Two Separate Regulatory Sites in the Retinal Cyclic Nucleotide-Gated Channel.
Resolution	N/A
Binding residue (original residue number in PDB)	E85 L113 E115 M145 M146
Binding residue (residue number reindexed from 1)	E4 L32 E34 M64 M65

Molecular Function

GO:0005509

calcium ion binding

GO:0005515

protein binding

GO:0010856

adenylate cyclase activator activity

GO:0019855

calcium channel inhibitor activity

GO:0019901

protein kinase binding

GO:0031432

titin binding

GO:0043539

protein serine/threonine kinase activator activity

GO:0044325

transmembrane transporter binding

GO:0046872

metal ion binding

GO:0048306

calcium-dependent protein binding

GO:0072542

protein phosphatase activator activity

	Biological Process
GO:0000086	G2/M transition of mitotic cell cycle
GO:0002027	regulation of heart rate
GO:0005513	detection of calcium ion
GO:0007186	G protein-coupled receptor signaling pathway
GO:0010800	positive regulation of peptidyl-threonine phosphorylation
GO:0010801	negative regulation of peptidyl-threonine phosphorylation
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0016240	autophagosome membrane docking
GO:0021762	substantia nigra development
GO:0031954	positive regulation of protein autophosphorylation
GO:0032465	regulation of cytokinesis
GO:0035458	cellular response to interferon-beta
GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT
GO:0050848	regulation of calcium-mediated signaling
GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity
GO:0051592	response to calcium ion
GO:0055117	regulation of cardiac muscle contraction
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity
GO:0071346	cellular response to type II interferon
GO:0071902	positive regulation of protein serine/threonine kinase activity
GO:0098901	regulation of cardiac muscle cell action potential
GO:0140056	organelle localization by membrane tethering
GO:0140238	presynaptic endocytosis
GO:1901020	negative regulation of calcium ion transmembrane transporter activity
GO:1901842	negative regulation of high voltage-gated calcium channel activity
GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction
GO:1905913	negative regulation of calcium ion export across plasma membrane
GO:1990456	mitochondrion-endoplasmic reticulum membrane tethering

Biological Process

GO:0000086

G2/M transition of mitotic cell cycle

GO:0002027

regulation of heart rate

GO:0005513

detection of calcium ion

GO:0007186

G protein-coupled receptor signaling pathway

GO:0010800

positive regulation of peptidyl-threonine phosphorylation

GO:0010801

negative regulation of peptidyl-threonine phosphorylation

GO:0010880

regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

GO:0010881

regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

GO:0016240

autophagosome membrane docking

GO:0021762

substantia nigra development

GO:0031954

positive regulation of protein autophosphorylation

GO:0032465

regulation of cytokinesis

GO:0035458

cellular response to interferon-beta

GO:0046427

positive regulation of receptor signaling pathway via JAK-STAT

GO:0050848

regulation of calcium-mediated signaling

GO:0051343

positive regulation of cyclic-nucleotide phosphodiesterase activity

GO:0051592

response to calcium ion

GO:0055117

regulation of cardiac muscle contraction

GO:0060314

regulation of ryanodine-sensitive calcium-release channel activity

GO:0060315

negative regulation of ryanodine-sensitive calcium-release channel activity

GO:0060316

positive regulation of ryanodine-sensitive calcium-release channel activity

GO:0071346

cellular response to type II interferon

GO:0071902

positive regulation of protein serine/threonine kinase activity

GO:0098901

regulation of cardiac muscle cell action potential

GO:0140056

organelle localization by membrane tethering

GO:0140238

presynaptic endocytosis

GO:1901020

negative regulation of calcium ion transmembrane transporter activity

GO:1901842

negative regulation of high voltage-gated calcium channel activity

GO:1901844

regulation of cell communication by electrical coupling involved in cardiac conduction

GO:1905913

negative regulation of calcium ion export across plasma membrane

GO:1990456

mitochondrion-endoplasmic reticulum membrane tethering

	Cellular Component
GO:0000922	spindle pole
GO:0005576	extracellular region
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0005819	spindle
GO:0005829	cytosol
GO:0005856	cytoskeleton
GO:0005876	spindle microtubule
GO:0005886	plasma membrane
GO:0008076	voltage-gated potassium channel complex
GO:0016020	membrane
GO:0030017	sarcomere
GO:0031514	motile cilium
GO:0031982	vesicle
GO:0032991	protein-containing complex
GO:0034704	calcium channel complex
GO:0043209	myelin sheath
GO:0044305	calyx of Held
GO:0097225	sperm midpiece
GO:0099523	presynaptic cytosol
GO:1902494	catalytic complex

Cellular Component

spindle pole

extracellular region

nucleus

nucleoplasm

cytoplasm