Structure of PDB 8df9 Chain A Binding Site BS01

Receptor Information
>8df9 Chain A (length=781) Species: 2320 (Methanopyrus kandleri) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALVYDAEFVGSEREFEEERETFLKGVKAYDGVLATRYLMERSSSAKNDEE
LLELHQNFILLTGSYACSIDPTEDRYQNVIVRGVNFDERVQRLSTGGSPA
RYAIVYRRGWRAIAKALDIDEEDVPAIEVRAVKRNPLQPALYRILVRYGR
VDLMPVTVDEVPPEMAGEFERLIERYDVPIDEKEERILEILRENPWTPHD
EIARRLGLSVSEVEGEKDPESSGIYSLWSRVVVNIEYDERTAKRHVKRRD
RLLEELYEHLEELSERYLRHPLTRRWIVEHKRDIMRRYLEQRIVECALKL
QDRYGIREDVALCLARAFDGSISMIATTPYRTLKDVCPDLTLEEAKSVNR
TLATLIDEHGLSPDAADELIEHFESIAGILATDLEEIERMYEEGRLSEEA
YRAAVEIQLAELTKKEGVGRKTAERLLRAFGNPERVKQLAREFEIEKLAS
VEGVGERVLRSLVPGYASLISIRGIDRERAERLLKKYGGYSKVREAGVEE
LREDGLTDAQIRELKGLKTLESIVGDLEKADELKRKYGSASAVRRLPVEE
LRELGFSDDEIAEIKGIPKKLREAFDLETAAELYERYGSLKEIGRRLSYD
DLLELGATPKAAAEIKERSEEEWKEWLERKVGEGRARRLIEYFGSAGEVG
KLVENAEVSKLLEVPGIGDEAVARLVPGYKTLRDAGLTPAEAERVLKRYG
SVSKVQEGATPDELRELGLGDAKIARILGLRSLVNARLDVDTAYELARRY
GSVSAVRAAPVAELRELGLSDRAIARIAGIP
Ligand information
Receptor-Ligand Complex Structure
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PDB8df9 Structures of topoisomerase V in complex with DNA reveal unusual DNA binding mode and novel relaxation mechanism.
Resolution3.24 Å
Binding residue
(original residue number in PDB)		G517 K519 T520 S540 A541 S542 W699 K703 S825
Binding residue
(residue number reindexed from 1)		G516 K518 T519 S539 A540 S541 W626 K630 S752
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:8df9, PDBe:8df9, PDBj:8df9
PDBsum8df9
PubMed35969036
UniProtQ977W1

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