Structure of PDB 8dex Chain A Binding Site BS01

Receptor Information
>8dex Chain A (length=220) Species: 882 (Nitratidesulfovibrio vulgaris str. Hildenborough) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TYGIRLRVWGDYACFTRPEMKVERVSYDVMPPSAARGILEAIHWKPAIRW
IVDRIHVLRPIVFDNVRRNEVSSKIPKPNPATAMRDRKPLYFLVDDGSNR
QQRAATLLRNVDYVIEAHFELTDKAGAEDNAGKHLDIFRRRARAGQSFQQ
PCLGCREFPASFELLEGDVPLSCYAGEKRDLGYMLLDIDFERDMTPLFFK
AVMEDGVITPPSRTSPEVRA
Ligand information
>8dex Chain L (length=48) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggauugaaacgccaugcucaggcuggcgagugcgcgccacucaucaag
................................................
Receptor-Ligand Complex Structure
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PDB8dex Structural snapshots of R-loop formation by a type I-C CRISPR Cascade.
Resolution2.7 Å
Binding residue
(original residue number in PDB)
T23 P25 K28 A41 R43 G44 E47 W51 R75 N76 E77 V78 V101 R107 Q109 F155 P158 C159 G161 R163 F197 P203
Binding residue
(residue number reindexed from 1)
T16 P18 K21 A34 R36 G37 E40 W44 R68 N69 E70 V71 V94 R100 Q102 F148 P151 C152 G154 R156 F190 P196
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

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Molecular Function

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Biological Process
External links
PDB RCSB:8dex, PDBe:8dex, PDBj:8dex
PDBsum8dex
PubMed36805026
UniProtQ72WF9

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