Structure of PDB 8daf Chain A Binding Site BS01

Receptor Information
>8daf Chain A (length=230) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PNVPELILQLLQLEPDEDQVRARILGSDQPAAFGLLCRMADQTFISIVDW
ARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQ
EVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSL
DLKFLNNHILVKDAQEKANAALLDYTLCHYPHSGDKFQQLLLCLVEVRAL
SMQAKEYLYHKHLGNEMPRNNLLIEMLQAK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8daf Comparison of activity, structure, and dynamics of SF-1 and LRH-1 complexed with small molecule modulators.
Resolution2.59 Å
Binding residue
(original residue number in PDB)		R281 Q294 M295 L451 E454 M455
Binding residue
(residue number reindexed from 1)		R52 Q65 M66 L222 E225 M226
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity

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Molecular Function
External links
PDB RCSB:8daf, PDBe:8daf, PDBj:8daf
PDBsum8daf
PubMed37328104
UniProtQ13285|STF1_HUMAN Steroidogenic factor 1 (Gene Name=NR5A1)

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