Structure of PDB 8d3m Chain A Binding Site BS01

Receptor Information
>8d3m Chain A (length=343) Species: 272558 (Halalkalibacterium halodurans C-125) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKKLLNTLYVTQPDTYLSLDGDNVVLLKEQEKLGRLPLHNLEAIVGFGYT
GASPALMGYCAERNISITFLTKNGRFLARVVGESRGNVVLRKTQYRISEN
DQESTKIARNFITGKVYNSKWMLERMTREHPLRVNVEQFKATSQLLSVMM
QEIRNCDSLESLRGWEGQAAINYNKVFDQMILQQKEEFAFHGRSRRPPKD
NVNAMLSFAYTLLANDVAAALETVGLDAYVGFMHQDRPGRASLALDLMEE
LRGLYADRFVLSLINRKEMTADGFYKKENGAVLMTDEARKTFLKAWQTKK
QEKITHPYLGEKMSWGLVPYVQALLLARFLRGDLDEYPPFLWK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8d3m PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation.
Resolution3.41 Å
Binding residue
(original residue number in PDB)
D14 Y49
Binding residue
(residue number reindexed from 1)
D14 Y49
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004520 DNA endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

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Molecular Function

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Biological Process
External links
PDB RCSB:8d3m, PDBe:8d3m, PDBj:8d3m
PDBsum8d3m
PubMed36272411
UniProtQ9KFX9

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