Structure of PDB 8d2o Chain A Binding Site BS01 |
| >8d2o Chain A (length=749) Species: 351607 (Acidothermus cellulolyticus 11B)
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GTVPVTWRLGVDVGERSIGLAAVSYEEDKPKEILAAVSWIHDGGVGDERS
GASRLALRGMARRARRLRRFRRARLRDLDMLLSELGWTPLPDKNVSPVDA
WLARKRLAEEYVVDETERRRLLGYAVSHMARHRGWRNPWTTIKDLKNLPQ
PSDSWERTRESLEARYSVSLEPGTVGQWAGYLLQRAPGIRLNPTQQSLSN
ATAFETRLRQEDVLWELRCIADVQGLPEDVVSNVIDAVFCQKRPSVPAER
IRPPLPALHEATGHPVVDRNLAILRKFLSSATMRWGPPQSIVVELARGAS
ESESTGYAAVALRDRLLSYGEKNGVAQVAVFRGGVTAEARRWLDISIERL
FSRVAIFAQSTSTKRLDRRHHAVDAVVLTTLTPGVAKTLADARSRRVSAE
FWRRPSTEEPQSPAYRQWKESCSGLGDLLISTAARDSIAVAAPLRLRPTG
ALHEETLRAFSEHTVGAAWKGAELRRIVEPEVYAAFLALTDPGGRFLKVS
PSEDVLPADENRHIVLSDRVLGPRDRVKLFPDDRGSIRVRGGAAYIASFH
HARVFRWGSSHSPSFALLRVSLADLAVAGLLRDGVDVFTAELPPWTPAWR
YASIALVKAVESGDAKQVGWLVPGDELDFGPEGVTTAAGDLSMFLKYFPE
RHWVVTGFEDDKRINLKPAFLSAEQAEVLRTERSDRPDTLTEAGEILAQF
FPRCWRATVAKVLCHPGLTVIRRTALGQPRWRRGHLPYSWRPWSADPWS |
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| PDB | 8d2o Coupled catalytic states and the role of metal coordination in Cas9 |
| Resolution | 2.66 Å |
Binding residue
(original residue number in PDB) | H47 D48 S59 R60 L61 A62 R64 R68 R69 R71 R72 L73 R74 F76 R78 R82 L96 D98 K99 N100 V101 S102 P103 W107 H134 R137 H138 R139 G140 W141 P144 P193 G194 I195 R196 L197 N198 T200 Q202 N212 Q253 K254 P256 P259 E261 H481 H486 R491 R497 K498 S501 S502 M505 R506 S524 P828 L829 R830 L831 R832 T834 G835 A836 L837 H838 L842 R843 A844 V924 R925 G969 V970 D971 F973 T1109 L1111 Q1113 R1115 W1116 R1117 H1120 L1121 P1122 |
Binding residue
(residue number reindexed from 1) | H41 D42 S53 R54 L55 A56 R58 R62 R63 R65 R66 L67 R68 F70 R72 R76 L90 D92 K93 N94 V95 S96 P97 W101 H128 R131 H132 R133 G134 W135 P138 P187 G188 I189 R190 L191 N192 T194 Q196 N200 Q241 K242 P244 P247 E249 H259 H264 R269 R275 K276 S279 S280 M283 R284 S302 P443 L444 R445 L446 R447 T449 G450 A451 L452 H453 L457 R458 A459 V539 R540 G584 V585 D586 F588 T724 L726 Q728 R730 W731 R732 H735 L736 P737 |
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| Enzyme Commision number |
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