Structure of PDB 8cv7 Chain A Binding Site BS01
Receptor Information
>8cv7 Chain A (length=109) Species:
9606
(Homo sapiens) [
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SEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDL
STVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVF
EFRYAKMPD
Ligand information
>8cv7 Chain D (length=12) Species:
32630
(synthetic construct) [
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WYGYWKVPKRKC
Receptor-Ligand Complex Structure
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PDB
8cv7
Peptide 2.2E in complex with BRD2-BD2
Resolution
1.6 Å
Binding residue
(original residue number in PDB)
A367 W370 V376 L381 N429 H433 D434 V435 A437 M438
Binding residue
(residue number reindexed from 1)
A21 W24 V30 L35 N83 H87 D88 V89 A91 M92
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:8cv7
,
PDBe:8cv7
,
PDBj:8cv7
PDBsum
8cv7
PubMed
37269828
UniProt
P25440
|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)
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