Structure of PDB 8cis Chain A Binding Site BS01

Receptor Information
>8cis Chain A (length=312) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQD
TKGFSTWLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRL
FFLQVKEGILNDDIYCPPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDK
LLPQRVLEQHKLNKDQWEERIQVWHEEHRGMLREDAVLEYLKIAQDLEMY
GVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFN
DKKFVIKPIDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIE
VQQMKAQAREEK
Ligand information
Receptor-Ligand Complex Structure
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PDB8cis The FERM domain of human moesin with two bound peptides identified by phage display
Resolution1.52 Å
Binding residue
(original residue number in PDB)
K27 F30 W43 L61 N62 K83 F84 E289 L290
Binding residue
(residue number reindexed from 1)
K26 F29 W42 L60 N61 K82 F83 E288 L289
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0008092 cytoskeletal protein binding
Cellular Component
GO:0005856 cytoskeleton

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Molecular Function

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Cellular Component
External links
PDB RCSB:8cis, PDBe:8cis, PDBj:8cis
PDBsum8cis
PubMed37866628
UniProtP26038|MOES_HUMAN Moesin (Gene Name=MSN)

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