Structure of PDB 8c84 Chain A Binding Site BS01

Receptor Information
>8c84 Chain A (length=90) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHS
NKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKK
Ligand information
Receptor-Ligand Complex Structure
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PDB8c84 Structural basis of myocyte enhancer factor-2 recruitment of class II histone deacetylases.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		G2 R3 K5 K31
Binding residue
(residue number reindexed from 1)		G1 R2 K4 K30
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0045944 positive regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:8c84, PDBe:8c84, PDBj:8c84
PDBsum8c84
PubMed38492719
UniProtQ14814|MEF2D_HUMAN Myocyte-specific enhancer factor 2D (Gene Name=MEF2D)

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