Structure of PDB 8c56 Chain A Binding Site BS01

Receptor Information
>8c56 Chain A (length=388) Species: 272633 (Malacoplasma penetrans HF-2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DKIKVIKVFEAFAGIGSQFKALKNIARSKNWEIQHSGMVEWFVDAIVSYV
AIHSKNFNPKIERLDRDILSISNDSKMPISEYGIKKINNTIKASYLNYAK
KHFNNLFDIKKVNKDNFPKNIDIFTYSFPCQDLSVQGLQKGIDKELNTRS
GLLWEIERILEEIKNSFSKEEMPKYLLMENVKNLLSHKNKKNYNTWLKQL
EKFGYKSKTYLLNSKNFDNCQNRERVFCLSIRDDYLEKTGFKFKELEKVK
NPPKKIKDILVDSSNYKYLNLNKYETTTFRETKSNIISRPLKNYTTFNSE
NYVYNINGIGPTLTASGANSRIKIETQQGVRYLTPLECFKYMQFDVNDFK
KVQSTNLISENKMIYIAGNSIPVKILEAIFNTLEFVNN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8c56 CpG underrepresentation and the bacterial CpG-specific DNA methyltransferase M.MpeI.
Resolution2.4 Å
Binding residue
(original residue number in PDB)
C135 Q136 S139 V140 Q141 G142 L143 E184 R228 R230 T287 S289 F302 N303 P316 T317 T319 A320 S321 G322 G373 N374
Binding residue
(residue number reindexed from 1)
C130 Q131 S134 V135 Q136 G137 L138 E179 R223 R225 T282 S284 F297 N298 P311 T312 T314 A315 S316 G317 G368 N369
Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Gene Ontology
Molecular Function
GO:0003886 DNA (cytosine-5-)-methyltransferase activity
GO:0008168 methyltransferase activity
Biological Process
GO:0009307 DNA restriction-modification system
GO:0032259 methylation

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8c56, PDBe:8c56, PDBj:8c56
PDBsum8c56
PubMed38966999
UniProtQ8EVR5

[Back to BioLiP]