Structure of PDB 8c46 Chain A Binding Site BS01

Receptor Information

>8c46 Chain A (length=409) Species: 358 (Agrobacterium tumefaciens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

LTVNGDRLWDSLMDMAKIGPGIAGGNNRRTLTDEDAEGRRLFQRWCEAAG
LTMGVDRMGTMFATRPGEDPEALPVYIGSHLDTQPTGGKFDGVLGVLAGL
EVVRSLNDLNIKTKHPIVVTNWSNEEGARFAPAMLASGVFAGIHDLDYAY
SRTDTDGKTYGEELKRIGWLGEEEVGARRMHAYFEYHIEQGPILEADGKQ
IGVVTHGQGLWWLEVTLTGKEAHTGSTPMAMRVNAGLAAARILEKVQEVA
MAHQPGAVAGVGQMIFTPNSRNVLPGKVVFTIDLRTPSQAKLDSMRAIFE
REVPAIAEELGVGCSIEAIGHFDPVTFDAVLVGRVRAAAERLGYSHMDII
SGAGHDACWTARVAPSTMIFCPCVDGLSHNEAEEISPEWAAAGCDVLLHA
VLETAEIVQ

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

8c46 Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8c46 Structural and biochemical characterisation of the N-carbamoyl-beta-alanine amidohydrolase from Rhizobium radiobacter MDC 8606.
Resolution	2.0 Å
Binding residue (original residue number in PDB)	H86 D97 H193
Binding residue (residue number reindexed from 1)	H80 D91 H187
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.5.1.6: beta-ureidopropionase.

Gene Ontology

	Molecular Function
GO:0016787	hydrolase activity
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
GO:0046872	metal ion binding

View graph for
Molecular Function

External links

PDB	RCSB:8c46, PDBe:8c46, PDBj:8c46
PDBsum	8c46
PubMed	37634202
UniProt	A0A8F7I7M8

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