Structure of PDB 8c3d Chain A Binding Site BS01

Receptor Information
>8c3d Chain A (length=215) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSP
QNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNP
TGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVY
YDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNK
NNACGIANLASFPKM
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8c3d Sulfonated Calpeptin is a promising drug candidate against SARS-CoV-2 infections
Resolution2.0 Å
Binding residue
(original residue number in PDB)		G23 C25 D61 G64 G65 G66
Binding residue
(residue number reindexed from 1)		G23 C25 D61 G64 G65 G66
Enzymatic activity
Enzyme Commision number 3.4.22.38: cathepsin K.
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:8c3d, PDBe:8c3d, PDBj:8c3d
PDBsum8c3d
PubMed37853179
UniProtP43235|CATK_HUMAN Cathepsin K (Gene Name=CTSK)

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