Structure of PDB 8c1j Chain A Binding Site BS01

Receptor Information
>8c1j Chain A (length=340) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDTWQDEEYFDSYGTLKLHLEMLADQPRTTKYHSVILQNKESLKDKVILD
VGCGTGIISLFCAHHARPKAVYAVEASDMAQHTSQLVLQNGFADTITVFQ
QKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDTWLKGDGIIWPT
TAALHLVPCSAEKDYHSKVLFWDNAYEFNLSALKSLAIKEFFSRPKSNHI
LKPEDCLSEPCTILQLDMRTVQVPDLETMRGELRFDIQKAGTLHGFTAWF
SVYFQSLEEGQPQQVLSTGPLHPTTHWKQTLFMMDDPVPVHTGDVVTGSV
VLQRNPVWRRHMSVSLSWVVTSALDPTSQRVGEKVFPIWR
Ligand information
>8c1j Chain B (length=6) Species: 2449148 (Spodoptera aff. frugiperda 1 BOLD-2017) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
EREFDK
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8c1j Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 in complex with RSF1_18-30
Resolution2.0 Å
Binding residue
(original residue number in PDB)		Q110 Y118 L123 E126 M127 E223 M225 T227 F231 R299 S302 H381 R415 H416 W444 R445
Binding residue
(residue number reindexed from 1)		Q5 Y13 L18 E21 M22 E118 M120 T122 F126 R194 S197 H276 R310 H311 W339 R340
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0016274 protein-arginine N-methyltransferase activity
Biological Process
GO:0018216 peptidyl-arginine methylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8c1j, PDBe:8c1j, PDBj:8c1j
PDBsum8c1j
PubMed
UniProtQ3UKX1

[Back to BioLiP]