Structure of PDB 8c0j Chain A Binding Site BS01

Receptor Information
>8c0j Chain A (length=200) Species: 67825 (Citrobacter rodentium) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DKIVIAIDAGHGGQDPGAIGPGGTREKNVTIAIARKLRTLLNADPMFKGV
LTRDGDYFISVMGRSDVARKQNANFLVSIHADAAPNRSATGASVWVLSND
PYLSQAVLDLQFGHSQRVGYDVATNMLGQLERIGSLHKRRPEHASLGVLR
SPDIPSVLVETGFISNHGEERLLASDEYQQRLAEAIYQGLRNYFQAHPLQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8c0j Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8c0j Activator-induced conformational changes regulate division-associated peptidoglycan amidases.
Resolution3.381 Å
Binding residue
(original residue number in PDB)		H200 E215 H269
Binding residue
(residue number reindexed from 1)		H11 E26 H80
Annotation score4
Enzymatic activity
Enzyme Commision number 3.5.1.28: N-acetylmuramoyl-L-alanine amidase.
Gene Ontology
Molecular Function
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity
Biological Process
GO:0009253 peptidoglycan catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8c0j, PDBe:8c0j, PDBj:8c0j
PDBsum8c0j
PubMed37276423
UniProtA0A482PQR2

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