Structure of PDB 8bx2 Chain A Binding Site BS01

Receptor Information
>8bx2 Chain A (length=100) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDMKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTISR
FEALQLSLKNMSKLRPLLEKWVEEADNNENLQEISKSETLVQARKRKRTS
Ligand information
Receptor-Ligand Complex Structure
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PDB8bx2 Crystal structure of Oct4-Soc2-UTF1 complex
Resolution3.14 Å
Binding residue
(original residue number in PDB)
R20 T26 Q27 Q44 T45 S48
Binding residue
(residue number reindexed from 1)
R21 T27 Q28 Q45 T46 S49
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:8bx2, PDBe:8bx2, PDBj:8bx2
PDBsum8bx2
PubMed
UniProtP20263|PO5F1_MOUSE POU domain, class 5, transcription factor 1 (Gene Name=Pou5f1)

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