Structure of PDB 8bv1 Chain A Binding Site BS01
Receptor Information
>8bv1 Chain A (length=155) Species:
9606
(Homo sapiens) [
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MAKVQVNNVVVLDNPSPFYNPFQFEITFECIEDLSEDLEWKIIYVGSAES
EEYDQVLDSVLVGPVPAGRHMFVFQADAPNPGLIPDADAVGVTVVLITCT
YRGQEFIRVGYYVNNEYTETELRENPPVKPDFSKLQRNILASNPRVTRFH
INWED
Ligand information
>8bv1 Chain N (length=11) Species:
32630
(synthetic construct) [
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EKIARLARRIA
Receptor-Ligand Complex Structure
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PDB
8bv1
Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach.
Resolution
2.834 Å
Binding residue
(original residue number in PDB)
A48 E51 D54 D88 V92 V94 R108 Y112 R145
Binding residue
(residue number reindexed from 1)
A48 E51 D54 D88 V92 V94 R108 Y112 R145
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0006325
chromatin organization
Cellular Component
GO:0005634
nucleus
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Biological Process
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Cellular Component
External links
PDB
RCSB:8bv1
,
PDBe:8bv1
,
PDBj:8bv1
PDBsum
8bv1
PubMed
37347155
UniProt
Q9Y294
|ASF1A_HUMAN Histone chaperone ASF1A (Gene Name=ASF1A)
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