Structure of PDB 8bux Chain A Binding Site BS01

Receptor Information

>8bux Chain A (length=289) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GAMGSEAVRSWRGAAEATSRLRERGCDGCLAGIEVQQLFCSQSAAIPEHQ
LKELNIKIDSALQAYKIALESLGHCEYAMKAGFHLNPKAIEASLQGCCSE
AEAQQTGRRPMQCELPTVPVQIGSHFLKGVSFNESAADNLKLKTHTMLQL
MKERDDFPVTEVLNQVCPSTWRGACKTAVQLLFGQAGLVVVDTAQIENKE
AYAPQISLEGSRIVVQVPSTWCLKEDPATMSLLQRSLDPEKTLGLVDVLY
TAVLDLNRWRAGREQALPCIQIQLQRGLQKTFSKLTSRF

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

8bux Chain A Residue 704 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8bux MiniBAR/KIAA0355 is a dual Rac and Rab effector that controls actin contractility and trafficking for successful ciliogenesis
Resolution	1.86 Å
Binding residue (original residue number in PDB)	E235 S238
Binding residue (residue number reindexed from 1)	E16 S19
Annotation score	4

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:8bux, PDBe:8bux, PDBj:8bux
PDBsum	8bux
PubMed
UniProt	O15063\|GRRE1_HUMAN Granule associated Rac and RHOG effector protein 1 (Gene Name=GARRE1)

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