Structure of PDB 8b9u Chain A Binding Site BS01
Receptor Information
>8b9u Chain A (length=141) Species:
83332
(Mycobacterium tuberculosis H37Rv) [
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FERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLES
LGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHN
YIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLL
Ligand information
>8b9u Chain C (length=5) Species:
1562372
(Nonomuraea sp. MJM5123) [
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LVAWG
Receptor-Ligand Complex Structure
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PDB
8b9u
Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival.
Resolution
2.25 Å
Binding residue
(original residue number in PDB)
E3 F5 L88 E89 L92
Binding residue
(residue number reindexed from 1)
E2 F4 L87 E88 L91
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:8b9u
,
PDBe:8b9u
,
PDBj:8b9u
PDBsum
8b9u
PubMed
37137307
UniProt
P9WPC9
|CLPC1_MYCTU ATP-dependent Clp protease ATP-binding subunit ClpC1 (Gene Name=clpC1)
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