Structure of PDB 8b1s Chain A Binding Site BS01

Receptor Information
>8b1s Chain A (length=244) Species: 186540 (Sudan ebolavirus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DTPSNSMRPVADDNIDHTSHTPNGVASAFILEATVNVISGPKVLMKQIPI
WLPLGIADQKTYSFDSTTAAIMLASYTITHFGKANNPLVRVNRLGQGIPD
HPLRLLRMGNQAFLQEFVLPPVQLPQYFTFDLTALKLVTQPLPAATWTDT
PSLRPGLSFHPKLRPVLLPGLTADKIQTIVNLMQDFKIVPIDPAKSIIGI
EVPELLVHKLTGKKMNGQPIIPVLLPKYIPISPGDLTMVITPDY
Ligand information
Ligand IDSAL
InChIInChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
InChIKeyYGSDEFSMJLZEOE-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=C(O)c1ccccc1O
OpenEye OEToolkits 1.5.0c1ccc(c(c1)C(=O)O)O
CACTVS 3.341OC(=O)c1ccccc1O
FormulaC7 H6 O3
Name2-HYDROXYBENZOIC ACID;
SALICYLIC ACID
ChEMBLCHEMBL424
DrugBankDB00936
ZINCZINC000000001554
PDB chain8b1s Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8b1s co-crystal of SUDV VP40 with salicylic acid
Resolution1.6 Å
Binding residue
(original residue number in PDB)		F157 L158 L213 R214 P290
Binding residue
(residue number reindexed from 1)		F113 L114 L163 R164 P226
Annotation score1
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8b1s, PDBe:8b1s, PDBj:8b1s
PDBsum8b1s
PubMed39100314
UniProtQ5XX06|VP40_EBOSU Matrix protein VP40 (Gene Name=VP40)

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