Structure of PDB 8b0v Chain A Binding Site BS01

Receptor Information
>8b0v Chain A (length=124) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLPVIGRVAADAPILAEQNIEESCRINPAFFNPRADYLLRVRGMSMKDIG
ILDGDLLAVHVTREARNGQVVVARIGEEVTVKRFKREGSKVWLLAENPEF
APIEVDLKEQELIIEGLSVGVIRR
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8b0v Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8b0v Structural investigations on the SOS response in Pseudomonas aeruginosa
Resolution1.7 Å
Binding residue
(original residue number in PDB)		R120 L136 R204
Binding residue
(residue number reindexed from 1)		R40 L56 R124
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.21.88: repressor LexA.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0009432 SOS response
GO:0045892 negative regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8b0v, PDBe:8b0v, PDBj:8b0v
PDBsum8b0v
PubMed
UniProtP37452|LEXA_PSEAE LexA repressor (Gene Name=lexA)

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