Structure of PDB 8b0a Chain A Binding Site BS01

Receptor Information
>8b0a Chain A (length=97) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVALFEDTNLAAIHAKRVTIMPKDIQLARRIRGER
Ligand information
>8b0a Chain I (length=149) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcagaatcccggtgccgaggccgctcaattggtcgtagacagctctagc
accgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaaggg
gattactccctagtctccaggcacgtgtcagatatatacatcgataggc
Receptor-Ligand Complex Structure
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PDB8b0a ALC1 slides asymmetrically PARylated nucleosomes away from DNA breaks
Resolution3.0 Å
Binding residue
(original residue number in PDB)		Y41 R42 T45 R63 R72 F84 V117 T118
Binding residue
(residue number reindexed from 1)		Y4 R5 T8 R26 R35 F47 V80 T81
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:8b0a, PDBe:8b0a, PDBj:8b0a
PDBsum8b0a
PubMed38307862
UniProtP84233|H32_XENLA Histone H3.2

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