Structure of PDB 8ay4 Chain A Binding Site BS01

Receptor Information
>8ay4 Chain A (length=269) Species: 12130 (rhinovirus A2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LVVPNINSSNPTTSNSAPALDAAETGHTSSVQPEDVIETRYVQTSQTRDE
MSLESFLGRSGCIHESKLEVTLANYNKENFTVWAINLQEMAQIRRKFELF
TYTRFDSEITLVPCISALSQDIGHITMQYMYVPPGAPVPNSRDDYAWQSG
TNASVFWQHGQAYPRFSLPFLSVASAYYMFYDGYDEQDQNYGTANTNNMG
SLCSRIVTEKHIHKVHIMTRIYHKAKHVKAWCPRPPRALEYTRAHRTNFK
IEDRSIQTAIVTRPIITTA
Ligand information
>8ay4 Chain D (length=25) Species: 12130 (rhinovirus A2) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AQVSRQNYFNINYFKDAASNGASKL
Receptor-Ligand Complex Structure
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PDB8ay4 Endosome rupture enables enteroviruses to infect cells.
Resolution4.7 Å
Binding residue
(original residue number in PDB)		D49 E54 D106 S167 K226 H227
Binding residue
(residue number reindexed from 1)		D49 E54 D106 S167 K226 H227
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:8ay4, PDBe:8ay4, PDBj:8ay4
PDBsum8ay4
PubMed
UniProtP04936|POLG_HRV2 Genome polyprotein

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