Structure of PDB 8att Chain A Binding Site BS01

Receptor Information
>8att Chain A (length=906) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALNIFNQDRQKVLENRATEAARERWKHDFEEAKARGDISIEKNLNVKLWK
WYNEMLPLVKEEINHCRSLLSEKLSDKKGLNKVDTNRLGYGPYLTLIDPG
KMCVITILELLKLNSTGGVIEGMRTARAVISVGKAIEMEFRSEQVLKSES
QAKILWPQSIRARIGSVLISMLIQVAKVSVQGVDPVTKAKVHGEAPAFAH
GYQYHNGSKLGVLKIHKTLIRQLNGERLIASVQPQLLPMLVEPKPWVNWR
SGGYHYTQSTLLRTKDSPEQVAYLKAASDNGDIDRVYDGLNVLGRTPWTV
NRKVFDVVSQVWNKGEGFLDIPGAQDEMVLPPAPPKNSDPSILRAWKLQV
KTIANKFSSDRSNRCDTNYKLEIARAFLGEKLYFPHNLDFRGRAYPLSPH
FNHLGNDMSRGLLIFWHGKKLGPSGLKWLKIHLSNLFGFDKLPLKDRVAF
TESHLQDIKDSAENPLTGDRWWTTADKPWQALATCFELNEVMKMDNPEEF
ISHQPVHQDGTCNGLQHYAALGGDVEGATQVNLVPSDKPQDVYAHVARLV
QKRLEIAAEKGDENAKILKDKITRKVVKQTVMTNVYGVTYVGATFQIAKQ
LSPIFDDRKESLDFSKYLTKHVFSAIRELFHSAHLIQDWLGESAKRISKS
IRLDVDEKSFKNGNKPDFMSSVIWTTPLGLPIVQPYREESKKQVETNLQT
VFISDPFAVNPVNARRQKAGLPPNFIHSLDASHMLLSAAECGKQGLDFAS
VHDSYWTHASDIDTMNVVLREQFIKLHEVDLVLRLKEEFDQRYKNYVKIG
KLKRSTDLAQKIIRIRKDLSRKLGRSTTLADEIYFEKKRQELLNSPLIED
RNVGEKMVTTVSLFEDITDLDALEGMSVLLPLRLPEIPPKGDFDVTVLRN
SQYFFS
Ligand information
Receptor-Ligand Complex Structure
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PDB8att Structures illustrate step-by-step mitochondrial transcription initiation
Resolution3.44 Å
Binding residue
(original residue number in PDB)		Y640 N642 G643 Y1026 V1027 K1052
Binding residue
(residue number reindexed from 1)		Y204 N206 G207 Y590 V591 K616
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0001018 mitochondrial promoter sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003896 DNA primase activity
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0000002 mitochondrial genome maintenance
GO:0006269 DNA replication, synthesis of primer
GO:0006351 DNA-templated transcription
GO:0006390 mitochondrial transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0034245 mitochondrial DNA-directed RNA polymerase complex
GO:0042645 mitochondrial nucleoid
GO:0043231 intracellular membrane-bounded organelle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8att, PDBe:8att, PDBj:8att
PDBsum8att
PubMed37821701
UniProtP13433|RPOM_YEAST DNA-directed RNA polymerase, mitochondrial (Gene Name=RPO41)

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