Structure of PDB 8asd Chain A Binding Site BS01 |
| >8asd Chain A (length=1826) Species: 992210 (SFTS virus AH12)
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MNLEVLCGRINVENGLSLGEPGLYDQIYDRPGLPDLDVTVDATGVTVDIG
AVPDSASQLGSSINAGLITIQLSEAYKINHDFTFSGLSKTTDRRLSEVFP
ITHDGSDGMTPAVIHTRLDGTIVVVEFSTTRSHNIGGLEAAYRTKIEKYR
DPISRRVDIMENPRVFFGVIVVSSGGVLSNMPLTQDEAEELMYRFCIANE
IYTKARSMDADIELQKSEEELEAISRALSFFSLFEPNIERVEGTFPNSEI
KMLEQFLSTPADVDFITKTLKAKEVEAYADLCDSHYLKPEKTIQERLEIN
RCEAIDKTQDLLAGLHARSNKQTSLNRGTVKLPPWLPKPSSESIDIKTDS
GFGSLMDHGAYGELWAKCLLDVSLGNVEGVVSDPAKELDIAISDDPEKDT
PKEAKITYRRFKPALSSSARQEFSLQGVEGKKWKRMAANQKKEKESHETL
SPFLDVEDIGDFLTFNNLLTDSRYGDESIQRAVSILLEKASAMQDTELTH
ALNDSFKRNLSSNVVQWSLWVSCLAQELASALKQHCRAGEFIIKKLKFWP
IYVIIKPTKSSSHIFYSLGIRKADVTRRLTGRVFSDTIDAGEWELTEFKS
LKTCKLTNLVNLPCTMLNSIAFWREKLGVAPWLVRKPCSELREQVGLTFL
ISLEDKSKTEEIITLTRYTQMEGFVSPPMLPKPQKMLGKLDGPLRTKLQV
YLLRKHLDCMVRIASQPFSLIPREGRVEWGGTFHAISGRSTNLENMVNSW
YIGYYKNKEESTELNALGEMYKKIVEMEEDKPSSPEFLGWGDTDSPKKHE
FSRSFLRAACSSLEREIAQRHGRQWKQNLEERVLREIGTKNILDLASMKA
TSNFSKDWELYSEVQTKEYHRSKLLEKMATLIEKGVMWYIDAVGQAWKAV
LDDGCMRICLFKKNQHGGLREIYVMDANARLVQFGVETMARCVCELSPHE
TVANPRLKNSIIENHGLKSARSLGPGSININSSNDAKKWNQGHYTTKLAL
VLCWFMPAKFHRFIWAAISMFRRKKMMVDLRFLAHLSSKSESRSSDPFRE
AMTDAFHGNRDVSWMDKGRTYIKTETGMMQGILHFTSSLLHSCVQSFYKS
YFVSKLKEGYMGESISGVVDVIEGSDDSAIMISIRPKSDMDEVRSRFFVA
NLLHSVKFLNPLFGIYSSEKSTVNTVYCVEYNSEFHFHRHLVRPTLRWIA
ASHQISETEALASRQEDYSNLLTQCLEGGASFSLTYLIQCAQLLHHYMLL
GLCLHPLFGTFMGMLISDPDPALGFFLMDNPAFAGGAGFRFNLWRACKTT
DLGRKYAYYFNEIQGKTKGDEDYRALDATSGGTLSHSVMVYWGDRKKYQA
LLNRMGLPEDWVEQIDENPGVLYRRAANKKELLLKLAEKVHSPGVTSSLS
KGHVVPRVVAAGVYLLSRHCFRFSSSIHGRGSTQKASLIKLLMMSSISAM
KHGGSLNPNQERMLFPQAQEYDRVCTLLEEVEHLTGKFVVRERNIVRSRI
DLFQEPVDLRCKAEDLVSEVWFGLKRTKLGPRLLKEEWDKLRASFAWLST
DPSETLRDGPFLSHVQFRNFIAHVDAKSRSVRLLGAPVVTTISQVVRMNF
FPGFSLESISILKHVLFMVLNGPYTEEYKLEMIIEAFSTLVIPQPSEVIR
KSRTMTLCLLSNYLSSRGGSILDQIERAQSGTLGGFSKPQKTFVRPGGGV
GYKGKGVWTGVMEDTHVQILIDGDGTSNWLEEIRLSSDARLYDVIESIRR
LCDDLGINNRVASAYRGHCMVRLSGFKIKPASRTDGCPVRIMVKMRVRGD
ILNLSVTIQEGRVMNILSYRPRDTDI |
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| PDB | 8asd Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein. |
| Resolution | 2.6 Å |
Binding residue
(original residue number in PDB) | S382 K386 E387 K405 Y408 E527 K533 Q534 K544 K849 A850 R871 F911 I922 Y923 V924 R930 R941 P955 G1081 H1084 N1220 L1254 Y1341 W1342 G1402 H1403 R1407 V1413 Y1414 R1418 C1420 K1435 H1573 K1577 R1582 |
Binding residue
(residue number reindexed from 1) | S382 K386 E387 K405 Y408 E527 K533 Q534 K544 K849 A850 R871 F911 I922 Y923 V924 R930 R941 P955 G1081 H1084 N1220 L1254 Y1341 W1342 G1402 H1403 R1407 V1413 Y1414 R1418 C1420 K1435 H1573 K1577 R1582 |
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| Enzyme Commision number |
2.7.7.48: RNA-directed RNA polymerase. |
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