Structure of PDB 8as7 Chain A Binding Site BS01 |
| >8as7 Chain A (length=1575) Species: 992210 (SFTS virus AH12)
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MNLEVLCGRINVENGLSLGEPGLYDQIYDRPGLPDLDVTVDATGVTVDIG
AVPDSASQLGSSINAGLITIQLSEAYKINHDFTFSGLSKTTDRRLSEVFP
ITHDGSDGMTPAVIHTRLDGTIVVVEFSTTRSHNIGGLEAAYRTKIEKYR
DPISRRVDIMENPRVFFGVIVVSSGGVLSNMPLTQDEAEELMYRFCIANE
IYTKARSMDADIELQKSEEELEAISRALSFFSLFEPNIERVEGTFPNSEI
KMLEQFLSTPADVDFITKTLKAKEVEAYADLCDSHYLKPEKTIQERLEIN
RCEAIDKTQDLLAGLHARSNKQTSLNRGTVKLPPWLPKPSSESIDIKTDS
GFGSLMDHGAYGELWAKCLLDVSLGNVEGVVSDPAKELDIAISAKITYRR
FKPALSSSARQEFSLQGVEGKKWKRMAANQKKEKESHETLSPFLDVEDIG
DFLTFNNLLTDSRYGDESIQRAVSILLEKASAMQDTELTHALNDSFKRNL
SSNVVQWSLWVSCLAQELASALKQHCRAGEFIIKKLKFWPIYVIIKPTKS
SSHIFYSLGIRKADVTRRLTGRVFSDTIDAGEWELTEFKSLKTCKLTNLV
NLPCTMLNSIAFWREKLGVAPWLVRKPCSELREQVGLTFLISLEDKSKTE
EIITLTRYTQMEGFVSPPMLPKPQKMLGKLDGPLRTKLQVYLLRKHLDCM
VRIASQPFSLIPREGRVEWGGTFHAISGRSTNLENMVNSWYIGYYKNKEE
STELNALGEMYKKIVEMEEDKPSSPEFLGWGDTDSPKKHEFSRSFLRAAC
SSLEREIAQRHGRQWKQNLEERVLREIGTKNILDLASMKATSNFSKDWEL
YSEVQTKEYHRSKLLEKMATLIEKGVMWYIDAVGQAWKAVLDDGCMRICL
FKKNQHGGLREIYVMDANARLVQFGVETMARCVCELSPHETVANPRLKNS
IIENHGLKSARSLGPGSININSSNDAKKWNQGHYTTKLALVLCWFMPAKF
HRFIWAAISMFRRKKMMVDLRFLAHLSSKSESRSSDPFREAMTDAFHGNR
DVSWMDKGRTYIKTETGMMQGILHFTSSLLHSCVQSFYKSYFVSKLKEGY
MGESISGVVDVIEGSDDSAIMISIRPKSDMDEVRSRFFVANLLHSVKFLN
PLFGIYSSEKSTVNTVYCVEYNSEFHFHRHLVRPTLRWIAASHQISETEA
LASRQEDYSNLLTQCLEGGASFSLTYLIQCAQLLHHYMLLGLCLHPLFGT
FMGMLISDPDPALGFFLMDNPAFAGGAGFRFNLWRACKTTDLGRKYAYYF
NEIQGKGTLSHSVMVYWGDRKKYQALLNRMGLPEDWVEQIDENPGVLYRR
AANKKELLLKLAEKVHSPGVTSSLSKGHVVPRVVAAGVYLLSRHCFRFSQ
KASLIKLLMMSSISAMKHGGSLNPNQERMLFPQAQEYDRVCTLLEEVEHL
TGKFVVRERNIVRSRIDLFQEPVDLRCKAEDLVSEVWFGLKRTKLGPRLL
KEEWDKLRASFAWLSTDPSETLRDGPFLSHVQFRNFIAHVDAKSRSVRLL
GAPVKKVTTISQVVRMNFFPGFSLE |
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| PDB | 8as7 Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein. |
| Resolution | 2.6 Å |
Binding residue
(original residue number in PDB) | R318 K331 Q426 G427 E429 K431 E443 K444 S446 H447 T449 H535 T558 K559 S562 H563 F565 S600 K602 K605 K656 R695 E763 L764 N765 F1032 H1035 S1044 S1045 R1049 |
Binding residue
(residue number reindexed from 1) | R318 K331 Q416 G417 E419 K421 E433 K434 S436 H437 T439 H525 T548 K549 S552 H553 F555 S590 K592 K595 K646 R685 E753 L754 N755 F1022 H1025 S1034 S1035 R1039 |
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| Enzyme Commision number |
2.7.7.48: RNA-directed RNA polymerase. |
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