Structure of PDB 8aq9 Chain A Binding Site BS01

Receptor Information
>8aq9 Chain A (length=44) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EKYCCEEASEKKCCPAGCKGDCKCANCHCAEQKQCGDKTHQHQG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8aq9 Chain A Residue 102 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8aq9 Juggling cadmium detoxification and zinc homeostasis: A division of labour between the two C. elegans metallothioneins.
ResolutionN/A
Binding residue
(original residue number in PDB)		C43 C54
Binding residue
(residue number reindexed from 1)		C18 C29
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0046870 cadmium ion binding
GO:0046872 metal ion binding
Biological Process
GO:0009408 response to heat
GO:0010288 response to lead ion
GO:0046686 response to cadmium ion
GO:0046689 response to mercury ion
GO:0071248 cellular response to metal ion
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8aq9, PDBe:8aq9, PDBj:8aq9
PDBsum8aq9
PubMed38151062
UniProtP17511|MT1_CAEEL Metallothionein-1 (Gene Name=mtl-1)

[Back to BioLiP]