Structure of PDB 8aq6 Chain A Binding Site BS01

Receptor Information
>8aq6 Chain A (length=171) Species: 727944 (Oplophorus gracilirostris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVFTLEDFVGDWRQTAGYNLDQVLEQGGVSSLFQNLGVSVTPIQRIVLSG
ENGLKIDIHVIIPYEGLSGDQMGQIEKIFKVVYPVDDHHFKVILHYGTLV
IDGVTPNMIDYFGRPYEGIAVFDGKKITVTGTLWNGNKIIDERLINPDGS
LLFRVTINGVTGWRLCERILA
Ligand information
Ligand IDOXY
InChIInChI=1S/O2/c1-2
InChIKeyMYMOFIZGZYHOMD-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		O=O
FormulaO2
NameOXYGEN MOLECULE
ChEMBLCHEMBL1234886
DrugBankDB09140
ZINC
PDB chain8aq6 Chain A Residue 205 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8aq6 Crystal structure of furimamide-bound NanoLuc luciferase
Resolution1.69 Å
Binding residue
(original residue number in PDB)		V7 V45 L46
Binding residue
(residue number reindexed from 1)		V9 V47 L48
Annotation score5
Enzymatic activity
Enzyme Commision number 1.13.12.13: Oplophorus-luciferin 2-monooxygenase.
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0033756 Oplophorus-luciferin 2-monooxygenase activity
Biological Process
GO:0008218 bioluminescence
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8aq6, PDBe:8aq6, PDBj:8aq6
PDBsum8aq6
PubMed38030625
UniProtQ9GV45|LUCI_OPLGR Oplophorus-luciferin 2-monooxygenase catalytic subunit

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