Structure of PDB 8age Chain A Binding Site BS01

Receptor Information
>8age Chain A (length=644) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SCVLSVFQTILKLVIFVAIFGAAISSRLFAVIKFESIIHEFDPWFNYRAT
KYLVNNSFYKFLNWFDDRTWYPLGRVTGGTLYPGLMTTSAFIWHALRNWL
GLPIDIRNVCVLFAPLFSGVTAWATYEFTKEIKDASAGLLAAGFIAIVPG
YISRSVAGSYDNEAIAITLLMVTFMFWIKAQKTGSIMHATCAALFYFYMV
SAWGGYVFITNLIPLHVFLLILMGRYSSKLYSAYTTWYAIGTVASMQIPF
VGFLPIRSNDHMAALGVFGLIQIVAFGDFVKGQIPIIASVSEHQPVSWPA
FFFDTHFLIWLFPAGVFLLFLDLKDEHVFVIAYSVLCSYFAGVMVRLMLT
LTPVICVSAAVALSKIFDIYLDFKKPAALLAKLIVSGSFIFYLYLFVFHS
TWVTRTAYSSPSVVLPSLIDDFREAYYWLRMNSDEDSKVAAWWDYGYQIG
GMADRTTLVDNNTWNNTHIAIVGKAMASPEEKSYEILKEHDVDYVLVIFG
GLIGFGGDDINKFLWMIRISEGIWPEEIKERDFYTAEGEYRVDARASETM
RNSLLYKMSYKDFPQLFNGGQATDRVRQQMITPLDVPPLDYFDEVFTSEN
WMVRIYQLKKDDAQGRTLRDVGELTRSSTKTRRSIKRPELGLRV
Ligand information
Receptor-Ligand Complex Structure
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PDB8age Molecular basis for glycan recognition and reaction priming of eukaryotic oligosaccharyltransferase.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		S347 V348 S349 W516 W517 D518 N535 W589
Binding residue
(residue number reindexed from 1)		S289 V290 S291 W442 W443 D444 N461 W515
Enzymatic activity
Enzyme Commision number 2.4.99.18: dolichyl-diphosphooligosaccharide--protein glycotransferase.
Gene Ontology
Molecular Function
GO:0004576 oligosaccharyl transferase activity
GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity
GO:0005515 protein binding
GO:0016757 glycosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006486 protein glycosylation
GO:0006487 protein N-linked glycosylation
GO:0018279 protein N-linked glycosylation via asparagine
GO:0043687 post-translational protein modification
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0008250 oligosaccharyltransferase complex
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8age, PDBe:8age, PDBj:8age
PDBsum8age
PubMed36435935
UniProtP39007|STT3_YEAST Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3 (Gene Name=STT3)

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