Structure of PDB 8aan Chain A Binding Site BS01

Receptor Information
>8aan Chain A (length=228) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TAVINHKKRKNSPRIVQSNDLTEAAYSLSRDQKRMLYLFVDQIRKSHDGI
CEIHVAKYAEIFGLTSAEASKDIRQALKSFAGKEVVFYYESFPWFIKPAH
SPSRGLYSVHINPYLIPFFIGLQNRFTQFRLSETKEITNPYAMRLYESLC
QYRKPDGSGIVSLKIDWIIERYQLPQSYQRMPDFRRRFLQVCVNEINSRT
PMRLSYIEKKKGRQTTHIVFSFRDITSM
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8aan Rep protein accommodates together dsDNA and ssDNA which enables a loop-back mechanism to plasmid DNA replication initiation.
Resolution2.19 Å
Binding residue
(original residue number in PDB)		R33 R200 M201 P202 R205 R206 R233 Q234
Binding residue
(residue number reindexed from 1)		R30 R180 M181 P182 R185 R186 R213 Q214
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0006276 plasmid maintenance
GO:0071897 DNA biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8aan, PDBe:8aan, PDBj:8aan
PDBsum8aan
PubMed37713613
UniProtP03856|REPE1_ECOLI Replication initiation protein (Gene Name=repE)

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