Structure of PDB 8aaj Chain A Binding Site BS01

Receptor Information
>8aaj Chain A (length=357) Species: 272844 (Pyrococcus abyssi GE5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVLTKDRIIEIIERKTGMSREEIEEEIRKIMEEDPYLSEQGAAALLAERL
GIDLIEKEEVSLMRISELYPGMDPREVNVVGRVLKKYPPREYTRKDGSVG
RVASLIIYDDSGRARVVLWDAKVSEYYNKIEVGDVIKVLDAQVKESLSGL
PELHINFRARIILNPDDPRVEMIPPLEEVRVATYTRKKIKDIEAGDRFVE
VRGTIAKVYRVLTYDACPECKKKVDYDEGLGVWICPEHGEVQPIKMTILD
FGLDDGTGYIRVTLFGDDAEELLGVSPEEIAEKIKELEESGLTTKEAARK
LAEDEFYNIIGREIVVRGNVIEDRFLGLILRASSWEDVDYRREIERIKEE
LEKLGVM
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8aaj Chain A Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8aaj DNA-binding mechanism and evolution of replication protein A.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		C218 C221 H239
Binding residue
(residue number reindexed from 1)		C217 C220 H238
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0010212 response to ionizing radiation

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Molecular Function
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Biological Process
External links
PDB RCSB:8aaj, PDBe:8aaj, PDBj:8aaj
PDBsum8aaj
PubMed37087464
UniProtQ9V1Y9

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