Structure of PDB 8a8x Chain A Binding Site BS01

Receptor Information
>8a8x Chain A (length=173) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HHMVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLA
SCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQLN
GGQYWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRV
NFQERVFPLFSVCSTGTYLRIWP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8a8x TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing.
Resolution2.37 Å
Binding residue
(original residue number in PDB)
N42 T43 R44 A69 F85 S158 C160
Binding residue
(residue number reindexed from 1)
N45 T46 R47 A72 F88 S161 C163
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:8a8x, PDBe:8a8x, PDBj:8a8x
PDBsum8a8x
PubMed35893676
UniProtQ9C029|TRIM7_HUMAN E3 ubiquitin-protein ligase TRIM7 (Gene Name=TRIM7)

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