Structure of PDB 8a78 Chain A Binding Site BS01

Receptor Information

>8a78 Chain A (length=335) Species: 80249 (Phaedon cochleariae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SKEESREFMAIFPDIVRDLTDAHTDIPEVTKRFAKVLQYNVPTGKKTRGL
STVIAYKMLEKPENLTPENVRLAGILGWCVELLQASLLIMDDLMDRSETR
RGQPCWYRQENVGFLAINDCLHVESSLYSVLRKYFSHLPCYVPIIELFHD
VNFKTNMGQSLDALCMKDGRPILSQFTMKRYSSIVKYKTSYYTFQLPVSL
GMYLADMYDPEQHRQAKTILMEIGEFAQIQDDFLDAFGDSKVGTDIKEGK
CSWLAVVALQRSNPAQRQIMEEHYGRPEPESTQIIKNLYIELGLPATFAV
YEEESFNIIRTHIHQISKGLPHDLFFKIMKKIYKR

Ligand information

Ligand ID

InChI

InChI=1S/Mn/q+2

InChIKey

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Name

MANGANESE (II) ION

PDB chain

8a78 Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	8a78 Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors.
Resolution	1.6 Å
Binding residue (original residue number in PDB)	D179 D183
Binding residue (residue number reindexed from 1)	D91 D95
Annotation score	1

Enzymatic activity

Enzyme Commision number

2.5.1.1: dimethylallyltranstransferase.

Gene Ontology

	Molecular Function
GO:0004659	prenyltransferase activity
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups

	Biological Process
GO:0008299	isoprenoid biosynthetic process

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:8a78, PDBe:8a78, PDBj:8a78
PDBsum	8a78
PubMed	37308711
UniProt	M1JS91

[Back to BioLiP]