Structure of PDB 8a6v Chain A Binding Site BS01

Receptor Information
>8a6v Chain A (length=342) Species: 80249 (Phaedon cochleariae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFSKEESREFMAIFPDIVRDLTDHTDIPEVTKRFAKVLQYNVPTGKKTRG
LSTVIAYKMLEKPENLTPENVRLAGILGWCVELLQASLLIMDDLMDRSET
RRGQPCWYRQENVGFLAINDCLHVESSLYSVLRKYFSHLPCYVPIIELFH
DVNFKTNMGQSLDALCMKDGRPILSQFTMKRYSSIVKYKTSYYTFQLPVS
LGMYLADMYDPEQHRQAKTILMEIGEFFQIQDDFLDAFGDSQVTGKVGTD
IKEGKCSWLAVVALQRSNPAQRQIMEEHYGRPEPESTQIIKNLYIELGLP
ATFAVYEEESFNIIRTHIHQISKGLPHDLFFKIMKKIYKRDA
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8a6v Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8a6v Metal-dependent enzyme symmetry guides the biosynthetic flux of terpene precursors.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		D179 D183
Binding residue
(residue number reindexed from 1)		D92 D96
Annotation score1
Enzymatic activity
Enzyme Commision number 2.5.1.1: dimethylallyltranstransferase.
Gene Ontology
Molecular Function
GO:0004659 prenyltransferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
Biological Process
GO:0008299 isoprenoid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8a6v, PDBe:8a6v, PDBj:8a6v
PDBsum8a6v
PubMed37308711
UniProtM1JS91

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