Structure of PDB 7zyh Chain A Binding Site BS01

Receptor Information
>7zyh Chain A (length=49) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KDCPWYDRGFCKHGPLCRHRHTRRVICVNYLVGFCPEGPSCKFMHPRFE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7zyh Chain A Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7zyh Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3' end biogenesis.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		C124 C132 C138 H142
Binding residue
(residue number reindexed from 1)		C3 C11 C17 H21
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7zyh, PDBe:7zyh, PDBj:7zyh
PDBsum7zyh
PubMed36073787
UniProtO95639|CPSF4_HUMAN Cleavage and polyadenylation specificity factor subunit 4 (Gene Name=CPSF4)

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