Structure of PDB 7zw4 Chain A Binding Site BS01

Receptor Information
>7zw4 Chain A (length=298) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KECDNALRQLETVRELLENPVQPINDMSYFGCLDSVMENSKVLGEAMTGI
SQNAKNGNLPEFGDAIATASKALCGFTEAAAQAAYLVGVSDPNSQAGQQG
LVEPTQFARANQAIQMACQSLGEPGCTQAQVLSAATIVAKHTSALCNSCR
LASARTANPTAKRQFVQSAKEVANSTANLVKTIKALDGDFTEENRAQCRA
ATAPLLEAVDNLSAFASNPEFSSVPAQISPEGRAAMEPIVISAKTMLESA
GGLIQTARALAVNPRDPPRWSVLAGHSRTVSDSIKKLITSMRDKAPGQ
Ligand information
>7zw4 Chain B (length=25) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
STKHILDDISTMFDALADQLDAMLD
Receptor-Ligand Complex Structure
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PDB7zw4 Crystal structure of Talin R7R8 domains with Caskin-2 LD-peptide
Resolution2.72 Å
Binding residue
(original residue number in PDB)
L1492 A1499 T1502 S1503 R1510 K1522 R1523 V1526 A1529 K1530 T1536 V1540 K1544
Binding residue
(residue number reindexed from 1)
L132 A139 T142 S143 R150 K162 R163 V166 A169 K170 T176 V180 K184
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:7zw4, PDBe:7zw4, PDBj:7zw4
PDBsum7zw4
PubMed38587458
UniProtP26039|TLN1_MOUSE Talin-1 (Gene Name=Tln1)

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