Structure of PDB 7zpy Chain A Binding Site BS01

Receptor Information
>7zpy Chain A (length=438) Species: 641809 (Influenza A virus (A/California/07/2009(H1N1))) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SIEPFLRTTPRPLRLPDGPLCHQRSKFLLMDALKLSIEDPSHEGEGIPLY
DAIKCMKTFFGWKEPNIVKPHEKGINPNYLMAWKQVLAELQDIENEEKIP
RTKNMKRTSQLKWALGENMAPEKSDEPEPRSLASWVQNEFNKACELTDSS
WIELDEIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMD
DFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLT
DPRLEPHKWEKYCVLEIGDMLLRTAIGQVSRPMFLYVRTNGTSKIKMKWG
MEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPRGV
EEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEP
GTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7zpy Thermodynamic and structural characterization of an optimized peptide-based inhibitor of the influenza polymerase PA-PB1 subunit interaction.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		Q408 N412 C415 E617 W619 P620 I621 G622 E623 K635 T639 L666 Q670 R673 N703 W706 F710
Binding residue
(residue number reindexed from 1)		Q137 N141 C144 E339 W341 P342 I343 G344 E345 K357 T361 L388 Q392 R395 N425 W428 F432
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:7zpy, PDBe:7zpy, PDBj:7zpy
PDBsum7zpy
PubMed36265804
UniProtC3W5X6

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