Structure of PDB 7zpp Chain A Binding Site BS01

Receptor Information
>7zpp Chain A (length=275) Species: 36374 (Visna/maedi virus EV1 KV1772) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IENIPLAEEEHNKWHQDAVSLHLEFGIPRTAAEDIVQQCDVCQENKMPST
LRGSNKRGIDHWQVDYTHYEDKIILVWVETNSGLIYAERVKGETGQEFRV
QTMKWYAMFAPKSLQSDNGPAFVAESTQLLMKYLGIEHTTGIPWNPQSQA
LVERTHQTLKNTLEKLIPMFNAFESALAGTLITLNIKRKGGLGTSPMDIF
IFNKEQQRIQQQSKSKQEKIRFCYYRTRKRGHPGEWQGPTQVLWGGDGAI
VVKDRGTDRYLVIANKDVKFIPPPK
Ligand information
Receptor-Ligand Complex Structure
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PDB7zpp A supramolecular assembly mediates lentiviral DNA integration
Resolution4.5 Å
Binding residue
(original residue number in PDB)		D18 K47 R231 H233
Binding residue
(residue number reindexed from 1)		D17 K46 R230 H232
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.4: ribonuclease H.
3.4.23.-
3.6.1.23: dUTP diphosphatase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:7zpp, PDBe:7zpp, PDBj:7zpp
PDBsum7zpp
PubMed28059770
UniProtP35956|POL_VILVK Gag-Pol polyprotein (Gene Name=pol)

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