Structure of PDB 7zmo Chain A Binding Site BS01

Receptor Information

>7zmo Chain A (length=441) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLC
YQLPALLAKGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKE
LLADLEREKPQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHC
VSQWGHDFRPDYLRLGALRSRLGHAPCVALTATATPQVQEDVFAALHLKK
PVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLKALGQEADKGLSGC
GIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVP
VIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRL
YYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEELGC
RHAAIAKYFGDALPACAKGCDHCQNPTAVRRRLEALERSSS

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

7zmo Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7zmo Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts
Resolution	3.75 Å
Binding residue (original residue number in PDB)	C427 C431 C434
Binding residue (residue number reindexed from 1)	C416 C420 C423
Annotation score	1

Enzymatic activity

Enzyme Commision number

5.6.2.4: DNA 3'-5' helicase.

Gene Ontology

	Molecular Function
GO:0003676	nucleic acid binding
GO:0004386	helicase activity
GO:0005524	ATP binding

	Biological Process
GO:0006310	DNA recombination

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Molecular Function

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Biological Process

External links

PDB	RCSB:7zmo, PDBe:7zmo, PDBj:7zmo
PDBsum	7zmo
PubMed
UniProt	O94762\|RECQ5_HUMAN ATP-dependent DNA helicase Q5 (Gene Name=RECQL5)

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