Structure of PDB 7zlg Chain A Binding Site BS01

Receptor Information
>7zlg Chain A (length=662) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YSQTWLASVVIIGLLVGYINYQHVYTLFENDKHFSHLADFEREMAYRTEM
GLYYSYYKTIINAPSFLEGVQEITHDTVTEHGHEINTLNRFNLYPEVILA
FLYRPFRAFAKSANWQIELCWQVNRGELRPVESCEGIGNPHYFYITGVFI
VAGTVASSIFYLGVLVSDSIFGGFLSVLCFAFNHGEATRVQWTPPLRESF
AFPFIIGHIAILTFVIKYKKSGHSMILLLTSMAVPALLFWQFTQFAFFTQ
ICSIFLAFSLDLIPFSTAKTVIHSHIISFLIGFLLLFGNEMMITALYFPS
ILALGMIIYISPLLSNLKFRPAYVLFLAIIFASITLGLKIGLSKGLGIED
DAHIFDILRSKFTSFANFHTRLYTCSAEFDFIQYSTIEKLCGTLLIPLAL
ISLVTFVFNFVKNTNLLWRNSEEIGENGEILYNVVQLCCSTVMAFLIMRL
KLFMTPHLCIVAALFANSKLLGGDRISKTIRVSALVGVIAILFYRGIPNI
RQQLNVKGEYSNPDQEMLFDWIQHNTKQDAVFAGTMPVMANVKLTTLRPI
VNHPHYEHVGIRERTLKVYSMFSKKPIAEVHKIMKEMGVNYFVFQLMNCS
NDERRPECVYRGMWDEEDPKNSGRTALCDLWILAANSKDNSRIAPFKIVY
NANRNYIVLKIL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7zlg Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase.
Resolution2.72 Å
Binding residue
(original residue number in PDB)		T70 T210 R211 W214 Y395 E400 R471 K473 P576
Binding residue
(residue number reindexed from 1)		T48 T188 R189 W192 Y373 E378 R449 K451 P554
Enzymatic activity
Enzyme Commision number 2.4.1.-
Gene Ontology
Molecular Function
GO:0000030 mannosyltransferase activity
GO:0016757 glycosyltransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0007399 nervous system development
GO:0018406 protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan
GO:0030154 cell differentiation
Cellular Component
GO:0005637 nuclear inner membrane
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0048471 perinuclear region of cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7zlg, PDBe:7zlg, PDBj:7zlg
PDBsum7zlg
PubMed36604564
UniProtP34413|DPY19_CAEEL C-mannosyltransferase dpy-19 (Gene Name=dpy-19)

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