Structure of PDB 7zj3 Chain A Binding Site BS01

Receptor Information
>7zj3 Chain A (length=86) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTL
SCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRTP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7zj3 Chain A Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7zj3 Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity.
Resolution2.53 Å
Binding residue
(original residue number in PDB)		C23 C26 C43 C46
Binding residue
(residue number reindexed from 1)		C15 C18 C35 C38
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:7zj3, PDBe:7zj3, PDBj:7zj3
PDBsum7zj3
PubMed36481767
UniProtQ9C040|TRIM2_HUMAN Tripartite motif-containing protein 2 (Gene Name=TRIM2)

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