Structure of PDB 7zc3 Chain A Binding Site BS01

Receptor Information
>7zc3 Chain A (length=67) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PKHEFSVDMTCGGCAEAVSRVLNKLGGVKYDIDLPNKKVCIESEHSMDTL
LATLKKTGKTVSYLGLE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7zc3 Chain A Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7zc3 Crystal Structure of the Human Copper Chaperone ATOX1 Bound to Zinc Ion.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		C12 C15
Binding residue
(residue number reindexed from 1)		C11 C14
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0005515 protein binding
GO:0016530 metallochaperone activity
GO:0016531 copper chaperone activity
GO:0032767 copper-dependent protein binding
GO:0046872 metal ion binding
GO:1903136 cuprous ion binding
Biological Process
GO:0006825 copper ion transport
GO:0006878 intracellular copper ion homeostasis
GO:0006979 response to oxidative stress
Cellular Component
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:7zc3, PDBe:7zc3, PDBj:7zc3
PDBsum7zc3
PubMed36291703
UniProtO00244|ATOX1_HUMAN Copper transport protein ATOX1 (Gene Name=ATOX1)

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