Structure of PDB 7zap Chain A Binding Site BS01
Receptor Information
>7zap Chain A (length=97) Species:
9606
(Homo sapiens) [
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MIDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNS
RRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAA
Ligand information
>7zap Chain B (length=28) [
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gggauuuccccaaaugugggaaacuccc
<<<<<<<<<<.......>>>>>>.>>>>
Receptor-Ligand Complex Structure
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PDB
7zap
Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39.
Resolution
N/A
Binding residue
(original residue number in PDB)
F156 M158 Q159 A161 R163 I164 R165 R183 I185 S186 D187 R188 N189 S190 R191 R192 S193 K194 I196 Y198 L219 V221
Binding residue
(residue number reindexed from 1)
F16 M18 Q19 A21 R23 I24 R25 R43 I45 S46 D47 R48 N49 S50 R51 R52 S53 K54 I56 Y58 L79 V81
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003676
nucleic acid binding
GO:0003723
RNA binding
Biological Process
GO:0006397
mRNA processing
Cellular Component
GO:0005634
nucleus
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Molecular Function
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Cellular Component
External links
PDB
RCSB:7zap
,
PDBe:7zap
,
PDBj:7zap
PDBsum
7zap
PubMed
37666821
UniProt
G3XAC6
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