Structure of PDB 7z8e Chain A Binding Site BS01

Receptor Information

>7z8e Chain A (length=590) Species: 382 (Sinorhizobium meliloti)

MEEQPVWHHATSSIGEPKYKDGFARFDYVNPDAPKGGELRLSESGTFDSF
NPILAKGEVATGVSSLVFETLLKSAEDEITTSYGLLAEGISYPDDISSAT
FRLRAEAKWADGKPVTPEDVVFSFDMVKEHNPLFSNYYRHVISAEKTGER
DVTFRFDEKNNHELPNILGQFPILPKHWWEGQDAKGSKRDISRTTLEPVM
GSGPYKIASFQAGGSIRFELRDDYWGKDLNVNVGRYNFRTINYAFFSDRS
VQFEAFRAGNVDFYQDNSASHWATAYDFPAMKDGRVIREEIENPLRATGI
MQAFVPNMRREKFKDQRVRQALNYAFDFEDLNRSLAHNAFQRVDSYFWGT
ELASSGLPEGREKEILEELKDKVPAAVFTTPYKNPVNGDPQKVRDNLRKA
LALFKEAGYELKGSRLVNAKTGEPFSFEILLSNPTFERTVTPFVNSVRKI
GIDARIRTVDDSQYTNRVRSYDYDMIYGIWAQTLVPGNEQSDYWGSASVN
QPGSRNYAGIADPAIDELIRRIVFAPNREELVATTRALDRVLLAHHYVVP
LFYSKALRVAYWNHLARPKELPYYGMDFPDAWWSKNTAAK

Ligand information

>7z8e Chain B (length=5) Species: 382 (Sinorhizobium meliloti)

GSDVA

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7z8e Dual-Uptake Mode of the Antibiotic Phazolicin Prevents Resistance Acquisition by Gram-Negative Bacteria.
• Resolution: 1.58 Å
• Binding residue (original residue number in PDB): N266 S267 A268 S269 Q301 F339 F435 R437 T438 Y476 Y552
• Binding residue (residue number reindexed from 1): N267 S268 A269 S270 Q302 F340 F436 R438 T439 Y477 Y553

Gene Ontology

Molecular Function

• GO:0046872 metal ion binding
• GO:1904680 peptide transmembrane transporter activity

Biological Process

• GO:0015833 peptide transport
• GO:0042884 microcin transport
• GO:0055085 transmembrane transport

Cellular Component

• GO:0030288 outer membrane-bounded periplasmic space
• GO:0042597 periplasmic space
• GO:0043190 ATP-binding cassette (ABC) transporter complex

External links

• PDB: RCSB:7z8e, PDBe:7z8e, PDBj:7z8e
• PDBsum: 7z8e
• PubMed: 36802165
• UniProt: A0A222JNH8