Structure of PDB 7z6g Chain A Binding Site BS01

Receptor Information

>7z6g Chain A (length=124) Species: 9913 (Bos taurus)

KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHES
LADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTT
QANKHIIVACEGNPYVPVHFDASV

Ligand information

• Ligand ID: F3I
• InChI: InChI=1S/C2H4O2.6H2O.2Rh/c1-2(3)4;;;;;;;;/h2H,1H3;6*1H2;;/q-2;;;;;;;2*+5/p-6
• InChIKey: VGUGBQHQEXDINJ-UHFFFAOYSA-H
• SMILES:
  OpenEye OEToolkits 2.0.7: CC1O[Rh+]([Rh+](O1)(O)(O)O)(O)(O)O
  CACTVS 3.385: CC(O[Rh+](O)(O)O)O[Rh+](O)(O)O
• Formula: C2 H10 O8 Rh2
• Name: (mi2-acetato-O, O')-hexaaquo-dirhodium (II)
• PDB chain: 7z6g Chain A Residue 201

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7z6g Reactivity of a fluorine-containing dirhodium tetracarboxylate compound with proteins
• Resolution: 1.71 Å
• Binding residue (original residue number in PDB): Y76 H105
• Binding residue (residue number reindexed from 1): Y76 H105
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 4.6.1.18: pancreatic ribonuclease.

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0004519 endonuclease activity
• GO:0004522 ribonuclease A activity
• GO:0004540 RNA nuclease activity
• GO:0005515 protein binding
• GO:0016829 lyase activity

Biological Process

• GO:0050830 defense response to Gram-positive bacterium

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:7z6g, PDBe:7z6g, PDBj:7z6g
• PDBsum: 7z6g
• UniProt: P61823|RNAS1_BOVIN Ribonuclease pancreatic (Gene Name=RNASE1)