Structure of PDB 7z6a Chain A Binding Site BS01

Receptor Information
>7z6a Chain A (length=332) Species: 1629 (Weissella viridescens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVLNLNDPQAVERYEEFMRQSPYGQVTQDLGWAKVKNNWEPVDVYLEDDQ
GAIIAAMSMLLGDTPTDKKFAYASKGPVMDVTDVDLLDRLVDEAVKALDG
RAYVLRFDPEVAYSDEFNTTLQDHGYVTRNRNVAAGMHATIQPRLNMVLD
LTKFPDAKTTLDLYPSKTKSKIKRPFRDGVEVHSGNSATELDEFFKTYTT
MAERHGITHRPIEYFQRMQAAFDADTMRIFVAEREGKLLSTGIALKYGRK
IWYMYAGSMDGNTYYAPYAVQSEMIQWALDTNTDLYDLGGIESESTDDSL
YVFKHVFVKDAPREYIGEIDKVLDPEVYAELV
Ligand information
Receptor-Ligand Complex Structure
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PDB7z6a Amino-acyl tXNA as inhibitors or amino acid donors in peptide synthesis.
Resolution1.66 Å
Binding residue
(original residue number in PDB)
W32 K36 M138 H139 I142 Q143 R211 Y215 Y256
Binding residue
(residue number reindexed from 1)
W32 K36 M137 H138 I141 Q142 R210 Y214 Y255
Enzymatic activity
Enzyme Commision number 2.3.2.10: UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase.
Gene Ontology
Molecular Function
GO:0016746 acyltransferase activity
GO:0016755 aminoacyltransferase activity
GO:0047206 UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase activity
Biological Process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0044038 cell wall macromolecule biosynthetic process
GO:0071555 cell wall organization

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Molecular Function

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Biological Process
External links
PDB RCSB:7z6a, PDBe:7z6a, PDBj:7z6a
PDBsum7z6a
PubMed36350642
UniProtQ9EY50|FEMX_WEIVI UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase (Gene Name=femX)

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